Gerald W. Dorn, II publications
- Chen Y, Dorn GW II. PINK1-phosphorylated mitofusin 2 is a Parkin receptor for culling damaged mitochondria. Science, 340:471-5, 2013. PMCID: PMC3774525.
- Gong G, Song M, Csordas G, Kelly DP, Matkovich SJ, Dorn GW II. Parkin-mediated mitophagy directs perinatal cardiac metabolic maturation in mice. Science, 350:aad2459, 2015. PMC4747105.
- Franco A, Kitsis RN, Fleischer JA, Gavathiotis E, Kornfeld OS, Gong G, Biris N, Benz A, Qvit N, Donnelly SK, Chen Y, Mennerick S, Hodgson L, Mochly-Rosen D, Dorn GW II. Correcting mitochondrial fusion by manipulating mitofusin conformations. Nature, 540:74-79, 2016. PMCID: 5315023.
- Rocha AG, Franco A, Krezel AM, Rumsey JM, Alberti JM, Knoght WC, Biris N, Zacharioudakis E, Janetka JW, Baloh RH, Kitsis RN, Mochly-Rosen D, Townsend RR, Gavathiotis E, Dorn GW II. Mfn2 agonists reverse mitochondrial defects in preclinical models of Charcot Marie Tooth disease type 2A. Science, 360:336-341, 2018.
- Franco A, Dang X, Walton EK, Ho JN, Zablocka B, Ly C, Miller TM, Baloh RH, Shy M, Yoo AS, Dorn GW II. Burst mitofusin activation reverses neuromuscular dysfunction in murine CMT2A. Elife, 9:e61119, 2020.
Complete list of Dr. Dorn’s publications »
John R. Edwards publications
- Matkovich SJ, Edwards JR, Grossenheider TC, de Guzman Strong C, Dorn GW 2nd. Epigenetic coordination of embryonic heart transcription by dynamically regulated long noncoding RNAs. Proc Natl Acad Sci U S A. 2014 Jul 28 (pdf).
- Cruickshanks HA, McBryan T, Shah PP, Nelson DM, Donahue G, VanderKraats ND, Edwards JR, Berger SL, Adams PD. Senescent cells harbour features of the cancer epigenome. Nature Cell Biology. 2013; 15:1495-1506.
- Li S, Shen D, Shao J, Crowder R, Liu W, Prat A, He X, Liu S, Hoog J, Lu C, Ding L, Griffith OL, Miller C, Larson D, Fulton RS, Harrison M, Mooney T, McMichael JF, Luo J, Tao Y, Goncalves R, Schlosberg C, Hiken JF, Saied L, Sanchez C, Giuntoli T, Bumb C, Cooper C, Kitchens RT, Lin A, Phommaly C, Davies SR, Zhang J, Kavuri MS, McEachern D, Dong YY, Ma C, Pluard T, Naughton M, Bose R, Suresh R, McDowell R, Michel L, Aft R, Gillanders W, DeSchryver K, Wilson RK, Wang S, Mills GB, Gonzalez-Angulo A, Edwards JR, Maher C, Perou CM, Mardis ER, Ellis MJ. Endocrine-therapy-resistant ESR1 variants revealed by genomic characterization of breast-cancer-derived xenografts. Cell Rep. 2013 Sep 26;4(6):1116-30.
- VanderKraats ND, Decker KF, Hiken JF, Edwards JR. Discovering high-resolution patterns of differential DNA methylation that correlate with gene expression changes. Nucleic Acids Res. 2013; 41:6816-6827 (pdf).
- Boulard M, Edwards JR, Bestor TH. FBXL10 protects polycomb-bound genes from hypermethylation. Nature Genetics 2015 (pdf).
Complete list of Dr. Edwards’ publications »
Scot J. Matkovich publications
- Matkovich SJ, Edwards JR, Grossenheider TC, de Guzman Strong C, Dorn GW 2nd. Epigenetic coordination of embryonic heart transcription by dynamically regulated long noncoding RNAs. Proc Natl Acad Sci U S A. 2014 Jul 28 (pdf).
- Chen Y, Sparks M, Bhandari P, Matkovich SJ, Dorn GW. Mitochondrial genome linearization is a causative factor for cardiomyopathy in mice and Drosophila. Antioxid Redox Signal. 2013 October 22 (pdf).
- Sullivan RP, Fogel LA, Leong JW, Schneider SE, Wong R, Romee R, Thai TH, Sexl V, Matkovich SJ, Dorn GW, II, French AR, Fehniger TA. MicroRNA-155 tunes both the threshold and extent of NK cell activation via targeting of multiple signaling pPathways. J Immunol. 2013;191:5904-13 (pdf).
- Aly H, Rohatgi N, Marshall CA, Grossenheider TC, Miyoshi H, Stappenbeck TS, Matkovich SJ, McDaniel ML. A novel strategy to increase the proliferative potential of adult human beta-cells while maintaining their differentiated phenotype. PLoS One 2013; 8(6):e66131.